Carolina Panthers running back Christian McCaffrey left Thursday's game against the Houston Texans for a sideline medical tent early in the second quarter.
He did not return to the field, and the Panthers ruled him out for the rest of the game with a hamstring injury.
McCaffrey appeared to suffer the injury on a two-yard run early in the second quarter. He pulled up and hopped on his right leg during the run before running out of bounds. A timetable for his recovery was not immediately clear.
The loss is a tough blow for McCaffrey and a Panthers team riding a hot start. McCaffrey missed all but three games last season with multiple injuries including a high ankle sprain and a separated shoulder. The former All-Pro who tallied 2,392 yards from scrimmage during his last healthy season in 2019 looked very much like his former self during the season's first two weeks.
McCaffrey tallied 170 yards on the ground and 154 receiving yards in two games for a league-best 324 yards from scrimmage. He had 31 rushing yards and nine receiving yards against the Texans before leaving Thursday's game.
The Panthers, meanwhile, are one of the league's early surprises with a 2-0 record entering Thursday thanks to the emergence of quarterback Sam Darnold alongside McCaffrey and defense that allowed a league-low 380 yards during the first two weeks of the season.
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