Of the four divisional round games in the 2022 NFL playoffs this weekend, all but one will be a rematch from the regular season. The lone matchup we didn't see earlier this year will be Titans vs. Bengals on Saturday. As the No. 1 seed in the NFL playoff picture out of the AFC, the Titans are well-rested, as is running back Derrick Henry, who will likely return after being out since Week 8. Henry's impending return has Tennessee as a 3.5-point favorite in the latest divisional round NFL odds at Caesars Sportsbook.
However, the last time these teams met was in the 2020 season, when the Bengals won outright at 7.5-point underdogs. With the stakes higher this time around, should you feel confident in backing Joe Burrow and co. with your divisional round NFL bets? Can the Titans cover one of the slimmest NFL spreads of the week? All of the divisional round NFL lines are listed below and SportsLine's advanced computer model has all the NFL betting advice and predictions you need to make the best divisional round NFL picks now.
The model, which simulates every NFL game 10,000 times, is up over $7,500 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters the divisional round of the 2021 NFL playoffs on an incredible 137-97 run on top-rated NFL picks that dates back to the 2017 season. Amazingly, it hasn't missed a top-rated pick since Week 14 of the regular season.
The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.
Now, it has turned its attention to the latest divisional round 2022 NFL odds and locked in picks for every NFL matchup. Head here to see every pick.
Top divisional round NFL predictions
One of the model's strongest divisional round picks is that the Buffalo Bills (+2) cover the spread against the Chiefs. Since losing both straight-up and against the spread to the Buccaneers in Week 14, the Bills have won their last five games and are 4-0-1 against the spread over those contests. On the other hand, Kansas City has failed to cover in two of its last three games.
Bills quarterback Josh Allen has averaged 59.6 rushing yards per game over his last five, which is cause for concern for the Chiefs' defense. While Kansas City has made strides defensively, it's hard to account for a quarterback scrambling for a first down, which is something Allen did four times in the Wild Card win over New England. During the regular season, the Chiefs allowed the most rushing touchdowns and sixth-most rushing yards to opposing quarterbacks.
The model says the Bills cover in over 50 percent of simulations. With Buffalo's run game also dominating the clock and limiting possessions, the model also says you should back the Under (54.5) in that game.
How to make divisional round NFL picks
The model has also made the call on who wins and covers in every other game on the divisional round NFL schedule, and it's calling for one team to cover in well over 50 percent of simulations. You can only get every pick for every game at SportsLine.
So which NFL picks can you make with confidence, and which team is a must-back? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned over $7,500 since its inception, and find out.
Divisional round NFL odds, spreads, lines, schedule, bracket
Saturday, Jan. 22
Sunday, Jan. 23
Rams at Buccaneers (-3, 48.5)
Bills at Chiefs (-2, 54.5)
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